Kuo-Wei CHANG

  • Publish Date：2026-07-09
  • Update Date：2026-07-13
  • Units：Department of Dentistry
CHANG
 
Kuo-Wei CHANG, Professor

Email: ckcw@nycu.edu.tw

Phone: +886-2-2826-7223

Office Location: Room 405, Dentistry Building

Specialties: Oral Pathology, Molecular Pathology, Oral Cancer Research, Cancer Biology
 
Education
  • Ph.D. in Pathology, Northwestern University, USA
  • Residency Training in Oral Pathology, Northwestern University, USA
  • Bachelor of Dental Surgery (B.D.S.), National Yang-Ming Medical College

Professional Experience
  • Dean, College of Dentistry, National Yang Ming Chiao Tung University
  • Director, Institute of Oral Biology, National Yang-Ming University
  • President, Chinese Academy of Oral Pathology
  • Board-Certified Specialist, Oral Pathology
  • Professor, Department of Dentistry, National Yang-Ming University
  • Associate Professor, Department of Dentistry, National Yang-Ming University
  • Teaching Assistant, Department of Dentistry, National Yang-Ming Medical College
  • Research Fellow, Department of Stomatology, Taipei Veterans General Hospital
  • Resident, Department of Dentistry, Veterans General Hospital

Honors & Achievements
  • Convener, Medical Engineering Program, Ministry of Science and Technology (2020–2022)
  • President's Award, International Association of Oral Pathologists (2018)

Representative Publications (Past 5 Years)
  1. Lin LH, Chang KW, Cheng HW, Liu CJ* (2026, Feb). Profilin-2 promotes tumor aggressiveness in oral squamous cell carcinoma via HDAC1 modulation: implications for EMT and targeted therapy. Br J Cancer, 134: 331-41. NSTC 110-2314-B-195-015-MY3.
  2. Chang SR, Chou CH, Liu CJ, Chang KW, Pan JH, Yen SL, Lin SC* (2026, Jan). The roles of CD24-Sec14 like lipid binding 2 (SEC14L2) axis in the neoplastic progression of oral squamous cell carcinomas. J Dent Sci, 21(1): 232-243. NSTC 111-2314-B-A49A-025-MY3.
  3. Chou CH, Chang KW, Hung WW, Wei MA, Liu CJ, Lin SC* (2026, Jan). Apoptosis-inducing factor mitochondria-associated 2 (AIFM2) promotes tumor progression and predicts poor prognosis in oral squamous cell carcinoma. J Dent Sci, 21(1): 541-550. NSTC 114-2811-B-A49A-002.
  4. Liu YC, Liu SY, Lin YC, Liu CJ, Chang KW, Lin SC* (2024, Sep). The disruption of NEAT1-miR-125b-5p-SLC1A5 cascade defines the oncogenicity and differential immune profile in head and neck squamous cell carcinoma. Cell Death Discovery, 10, 392. NSTC 110-2314-B-A49A-521-MY3.
  5. Chang SR, Chou CH, Tu HF, Liu CJ, Chang KW*, Lin SC* (2024, Jul). The expression of immune co-stimulators as a prognostic predictor of head and neck squamous cell carcinomas and oral squamous cell carcinomas. J Dent Sci, 19(3):1380-1388. NSTC 108-2314-B-010-010-MY3. (Corresponding author)
  6. Chou CH, Yen CH, Liu CJ, Tu HF, Lin SC*, Chang KW* (2024, Mar). The upregulation of VGF enhances the progression of oral squamous carcinoma. Cancer Cell International, 24(1):115. NSTC 108-2314-B-010-010-MY3. (Corresponding author)
  7. Cheng YC, Chang, KW (co-first author), Pan JH, Chen CY, Chou CH, Tu HF, Li WC, Lin SC* (2023, Nov). Cold atmospheric plasma jet irradiation decreases the survival and the expression of oncogenic miRNAs of oral carcinoma cells. Int J Mol Sci, 24, 16662. NSTC 110-2314-B-A49A-515-MY3. (First author)
  8. Lin LH, Chang KW (co-first author), Cheng HW, Liu CJ* (2023, Aug). Identification of somatic mutations in plasma cell-free DNA from patients with metastatic oral squamous cell carcinoma. Int J Mol Sci, 24(12):10408. (First author)
  9. Chang SR, Chou CH, Liu CJ, Lin YC, Tu HF, Chang KW*, Lin SC* (2023, Apr). The concordant disruption of B7/CD28 immune regulators predicts the prognosis of oral carcinomas. Int J Mol Sci, 24(6): 5931. NSTC 110-2314-B-195-015-MY3. (Corresponding author)
  10. Lin SC., Liu CJ, Ji SH, Hung WW, Liu YC, Chang SR, Tu HF, Chang KW* (2022, Feb). The upregulation of oncogenic miRNAs in swabbed samples obtained from oral premalignant and malignant lesions. Clin Oral Investig, 26: 1343-51. MOST 107-2314-B-010-032-MY3. (Corresponding author)
  11. Chou CH, Fan Chiang CY, Yang CC, Liu YC, Chang SR, Chang KW*, Lin SC* (2021, Oct). miR-31-NUMB cascade modulates Monocarboxylate Transporters to increase oncogenicity and lactate production of oral carcinoma cells. Int J Mol Sci, 22(21):11731. MOST 107-2314-B-010-026-MY3. (Corresponding author)
  12. Chang KW, Hung WW, Chou CH, Tu HF, Chang SR, Liu YC, Liu CJ, Lin SC* (2021, Aug). LncRNA MIR31HG drives oncogenicity by inhibiting the Limb-Bud and Heart Development gene (LBH) during oral carcinoma. Int J Mol Sci, 21(8383):1-15. MOST 108-2314-B-010-011-MY3. (First author)
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