Professor Yuan-Min Lin
D.D.S,. M.Sc.(Hons), Ph.D.
ymlin@nycu.edu.tw

Chairperson and Professor, Department of Dentistry
National Yang Ming Chiao Tung University


Contact information
Room 423
Department of Dentistry
National Yang Ming Chiao Tung University
No 155, Sec 2, Li-Nong Street, Taipei, Taiwan
Phone: (+886)98861609
Office: (+886)2 28267301







Education

PhD in Chemical Engineering, 2004~2010
Imperial College London, UK

MSc (hons) in Biomedical Materials, 2003~2004
Queen Mary, University of London, UK

DDS, Doctor of Dental surgery, 1993~2000
National Yang-Ming University, Taiwan

Working Experience

Chairperson 2025~
Department of Dentistry
Director and Professor 2022~2025
Institute of oral tissue engineering and biomaterials
Professor, 2021~
Department of Dentistry, National Yang Ming Chiao Tung University
Specialist, 2019~
Operative Dentistry
Founder, 2017~
Enlighten Materials (www.enlightenmaterials.com)
Associate Professor, 2017~2021
National Yang-Ming University, Taiwan
Assistant Professor, 2010~2017
National Yang-Ming University, Taiwan
Deputy Secretary General, 2015~
Alumni Association of National Yang-Ming University
Deputy Secretary General, 2015~
Association for Dental Sciences of Republic of China
Reviewer, 2010~
Journal of Dental Science, Biomatter, Journal of Tissue Engineering and Regenerative Medicine, Reactive and functional polymer, Journal of polymer research, Polymers…
Director, 2008~2010
Arts Dental Clinic
Visiting Doctors, 2010~
Department of Stomatology, Veterans General Hospital, Taipei

Research Interests

Synthesis of light-cured resins for 3D printing
3D printing of bone replacement
Light-cured materials for cell encapsulation
Regenerative dental materials
Bioprinting
Tissue engineering and regenerative dentistry
Polyurethane materials for dental devices


Spinoff company from my laboratory
Enlighten Materials (www.enlightenmaterials.com)
Enlighten Materials (陽明數位牙材) is a leading biomedical venture from Taiwan that specializes in developing world-class dental 3D printing resins. Founded in 2017 as a spin-off from National Yang-Ming University, the company blends expertise from chemical engineering, organic chemistry, software development, and clinical dentistry. The company aims to lower the barrier to digital dentistry by providing high-quality, bio-compatible, and affordable materials. In 2020, Enlighten Materials achieved international recognition when its flagship products—such as temporary crown resins (AA Temp) and denture base resins (BB Base)—received US FDA 510(k) clearance, making it one of the earliest firms in Taiwan to secure this standard. Their diverse product lineup also includes surgical guides, custom trays, and water-washable models compatible with major SLA, DLP, and LCD 3D printers. By delivering high strength, low shrinkage, and exceptional precision, Enlighten Materials serves as a highly trusted original design manufacturer (ODM) partner for modern dental labs and clinics worldwide.

Mobile digital dental laboratory

The Mobile digital dental laboratory developed by Professor Yuan-Min Lin at the Department of Dentistry, National Yang Ming Chiao Tung University, is an innovative mobile setup designed to overcome geographical barriers in dental healthcare. 

Overview and Purpose
Remote Access: Built to provide comprehensive digital dental laboratory support in remote and mountainous regions where advanced prosthodontic care is scarce.
On-Site Production: Integrates a high-precision dental CNC (Computer Numerical Control) milling machine directly into a mobile vehicle or unit.
Streamlined Care: Enables immediate creation of precision restorations like single ceramic crowns on the spot, drastically reducing patient wait times and travel burdens.




Publications

1
Liu MR, Chen H, Tsou NT, Lee SY, Lin YM. 4D Printing of TBCHA-Based Shape Memory Polymer Composites: Bioglass 45S5 Addition Improves Stability Retention and Shape Memory Performance. ACS Omega. 2026 May 12;11(18):27063-27082. doi: 10.1021/acsomega.6c00690

2
Wu CJ, Lin YM, Chen H. Eliminating Cracks in 3D-Printed Ceramics Using Sacrificial Polyethylene Wax Microspheres in Photocurable Slurries. Ceramics International. 2025 Sep 9;51(27):53715-53727. doi: 10.1016/j.ceramint.2025.09.116

3
Yu-Hung Lu, Yuan-Min Lin*, Shyh-Yuan Lee, Hsuan Chen, High-Performance biocompatible shape memory polymers for 4D Printing: Effects of 4-tert-Butylcyclohexyl acrylate as a soft component monomer, European Polymer Journal, Volume 238, 2025,114228 (* Co-first author)

4
Hsuan Chen, Pey-Fen Tang, Shyh-Yuan Lee, Yuan-Min Lin (2024, Dec). Accuracy of single ceramic crowns milled on a mobile digital dental laboratory after transportation over varying distances. Journal of Dental Science, Volume 20, Issue 2, 2025, Pages 1008-1015,

5
Hsuan Chen, Wen-Liang Lo, Shyh-Yuan Lee, Yuan-Min Lin (2024, Apr). Controlling sintering temperature for biphasic calcium phosphate scaffolds using submicron hydroxyapatite slurries for LCD 3D printing. Ceramics International, Volume 50, Issue 7, Part A, 1 April 2024, Pages 11060-11074

6
Hsuan Chen, Jun-Pin Hou, Shyh-Yuan Lee, Yuan-Min Lin (2024, Jan). Effects of postpolymerization time and temperature on the flexural properties and hardness profile of three-dimensional printed provisional resin. Journal of dental science, Volume 19, Issue 1, January 2024, Pages 455-460.

7
Hsuan Chen,Chih-Hsin Lin, Shu-Wen Hung, Shyh-Yuan Lee and Yuan-Min Lin (2023, Nov). Effects of Acetyl Tributyl Citrate on the Mechanical Properties, Abrasion Resistance, and Cytotoxicity of the Light-Cured 3D Printing Polyurethane Resins. 3D Printing and Additive Manufacturing, https://doi.org/10.1089/3dp.2023.0161

8
Chen CC, Wu YF, Aung LM, Lin JC, Ngo ST, Su JN, Lin YM, Chang WJ. Automatic recognition of teeth and periodontal bone loss measurement in digital radiographs using deep-learning artificial intelligence. J Dent Sci. 2023 Jul;18(3):1301-1309. doi: 10.1016/j.jds.2023.03.020. Epub 2023 Apr 10. PMID: 37404656; PMCID: PMC10316502.

9
Hsuan Chen, Jun-Pin Hou, Shyh-Yuan Lee, Yuan-Min Lin, Effects of postpolymerization time and temperature on the flexural properties and hardness profile of three-dimensional printed provisional resin, Journal of Dental Sciences, Volume 19, Issue 1, 2024, Pages 455-460,

10
Chen H, Lin YM, Bupphathong S, Lim J, Huang JE, Huang W, Hsieh TAS, Lin CH. Synthesis of Silanized Bioactive Glass/Gelatin Methacrylate (GelMA/Si-BG) composite hydrogel for Bone Tissue Engineering Application. J Mech Behav Biomed Mater. 2023 Sep 30;147:106159. doi: 10.1016/j.jmbbm.2023.106159. Epub ahead of print. PMID: 37797555.

11
Chen H, Cheng DH, Huang SC, Lin YM. Comparison of flexural properties and cytotoxicity of interim materials printed from mono-LCD and DLP 3D printers. J Prosthet Dent. 2021 Nov;126(5):703-708. doi: 10.1016/j.prosdent.2020.09.003. Epub 2020 Oct 9. PMID: 33041074.
12
Chen, H.; Lee, S.-Y.; Lin, Y.-M. Synthesis and Formulation of PCL-Based Urethane Acrylates for DLP 3D Printers. Polymers 2020, 12, 1500.

13
Lin, Y.-M., Chen, H., Lin, C.-H., Huang, P.-J. and Lee, S.-Y. (2020), "Development of polycaprolactone/hydroxyapatite composite resin for 405 nm digital light projection 3D printing", Rapid Prototyping Journal, Vol. 26 No. 5, pp. 951-958.

14
Chih-Hsin Lin, Yuan-Min Lin (co-first author), Yu-Lin Lai and Shyh-Yuan Lee, Mechanical properties, accuracy, and cytotoxicity of UV-polymerized 3D printing resins composed of BisEMA, UDMA, and/or TEGDMA, Journal of Prosthetic Dentistry, 2020, vol 123(2)

15
Chih‐Hsin Lin, Jimmy Jiun‐Ming Su, Shyh‐Yuan Lee, Yuan‐Min Lin*, Stiffness Modification of Photopolymerizable Gelatin‐Methacrylate Hydrogels Influences Endothelial Differentiation of Human Mesenchymal Stem Cells. Journal of Tissue Engineering and Regenerative Medicine, 2018 Oct;12(10):2099-2111

16
Shyh-Yuan Lee, Sheng-Chien Wu, Hsuan Chen, and Yuan-Min Lin*, “Synthesis and Characterization of Polycaprolactone-Based Polyurethanes for the Fabrication of Elastic Guided Bone Regeneration Membrane,” BioMed Research International, vol. 2018, Article ID 3240571, 13 pages, 2018. https://doi.org/10.1155/2018/3240571.

17
Jy-Jiunn Tzeng, Yi-Ting Hsiao, Yun-Ching Wu, Hsuan Chen, Shyh-Yuan Lee, and Yuan-Min Lin*, “Synthesis, Characterization, and Visible Light Curing Capacity of Polycaprolactone Acrylate,” BioMed Research International, vol. 2018, Article ID 8719624, 8 pages, 2018. https://doi.org/10.1155/2018/8719624.

18
Chang, Wei-Ting; Hsu, Huang Jan; Jiang, Cho-Pei; Lee, Shyh-Yuan; Lin, Yuan-Min＊ "Effects of titanium dioxide and tartrazine lake on Z-axis resolution and physical properties of resins printed by visible-light 3D printers", Rapid Prototyping Journal, 2018, Vol. 24 Issue: 1, pp.160-165

19
Chih-Hsin Lin, Ming-Chau Chang, Shih-Chieh Hung, Shyh-Yuan Lee, Yuan-Min Lin*, Bioactive surface modification of polycaprolactone using MG63-conditioned medium can induce osteogenic differentiation of mesenchymal stem cells , Journal of Materials Science, 2017. 52(7):p3967-3978

20
Yung‐Chang Cheng*, Deng‐Huei Lin, Cho‐Pei Jiang, Yuan‐Min Lin*, Dental implant customization using numerical optimization design and 3‐dimensional printing fabrication of zirconia ceramic, International Journal for Numerical Methods in Biomedical Engineering, doi: 10.1002/cnm.2820.

21
Chih-Hsin Lin, Kai-Fung Lin, Kwei Mar, Shyh-Yuan Lee, Yuan-Min Lin*, Antioxidant N-acetylcysteine and glutathione increase the viability and proliferation of MG63 cells encapsulated in the gelatin-methacrylate/VA-086/blue light hydrogel system, Tissue Engineering, 2016, 22(8):p792-800

22
Chih-Hsin Lin, Shyh-Yuan Lee, Yuan-Min Lin*, Plasma treatment in conjunction with EGM-2 medium increases endothelial and osteogenic marker expressions of bone marrow mesenchymal stem cells, Journal of Materials Science, 2016. 51(19):p.9145-9154
23
Yung-Chang Cheng, Deng-Huei Lin, Cho-Pei Jiang, Yuan-Min Lin, Dental implant customization using numerical optimization design and 3‐dimensional printing fabrication of zirconia ceramic, International Journal of Numerical Methods in Biomedical Engineering, 2016, doi: 10.1002/cnm.2820

24
Lin Kai-Fung, Hsu Huang-Jan, Chang Shinn-Liang, Jiang Cho-Pei, Lin Yuan-min, Lee Shyh-Yuan, MG63 cells can survive and proliferate well when they are encapsulated in UV-cured gelatin-methacrylate hydrogel, IEEE IES ICIT2016 (EI)

25
Yung-Hsin Yeh, Chi-Tai Kuo, Yun-Shien Lee, Yuan-Min Lin, Stanley Nattel, Feng-Chun Tsai, Wei-Jan Chen, Regional-specific gene expression profiles in the left atria of patients with valvular atrial fibrillation. Heart Rhythm, 2013 Mar;10(3):p.383-91

26
Feng-Chun Tsai, Gwo-Jyh Chang, Yu-Juei Hsu, Yuan-Min Lin, Yun-Shien Lee, Wei-Jan Chen, Chi-Tai Kuo, Yung-Hsin Yeh, Proinflammatory gene expression in patients undergoing mitral valve surgery and Maze ablation for atrial fibrillation. Journal of Thoracic and Cardiovascular Surgery, 2016 Jun;151(6):1673-1682

27
Lin, Y.M., A. Zhang, H.J. Rippon, A. Bismarck, and A.E. Bishop, Tissue engineering of lung: the effect of extracellular matrix on the differentiation of embryonic stem cells to pneumocytes. Tissue Eng Part A, 2010. 16(5): p. 1515-26

28
Yuan-Min Lin, Wojciech Chrzanowski, Jonathan Knowles, Alexander Bismarck, Anne Bishop, Functionalized Poly(D,L-lactide) for pulmonary epithelial cell culture. Advanced Engineering Materials, volume 12(4): B101- B112 (in the new Advanced biomaterials section)

29
Yuan Min Lin, A. Zhang, A. Bismarck, A. E. Bishop, Effects of fibroblast growth factors on the differentiation of the pulmonary progenitors from murine embryonic stem cells. Exp Lung Res, 2010.36(5):p.307‐20

30
Emilija Fidancevska, Gordana Ruseska, Joerg Bossert, Yuan-Min Lin, Aldo R. Boccaccini, Fabrication and Characterization of Porous Bioceramic Composites Based on Hydroxyapatite and Titania. Materials Chemistry and Physics 103(1):95-100 · May 2007