SHAN-LING HUNG

  • Publish Date：2026-07-14
  • Update Date：2026-07-15
  • Units：College of Dentistry
shan ling huan
Shan-Ling Hung, Professor

Tel: (+886)-2-2826-7224
Fax: (+886)-2-2826-4053
E-mail: slhung22@nycu.edu.tw

Fields of Specialty:
Oral Microbiology, Virology, Molecular Biology





Education
PhD, Molecular Biology Graduate Group, Program in Microbiology, University of Pennsylvania, PA, USA

Key Publications
  1. Wu C-Y, Yu Z-Y, Hsu Y-C, Hung S-L*. Enhancing production of herpes simplex virus type 1 in oral epithelial cells by co-infection with Aggregatibacter actinomycetemcomitans. Journal of the Formosan Medical Association 2022; 121(9): 1841-1849.
  2. Wu C-Y, Yu Z-Y, Chen Y-C, Hung S-L*. Effects of epigallocatechin-3-gallate and acyclovir on herpes simplex virus type 1 infection in oral epithelial cells. Journal of the Formosan Medical Association 2021; 120(12): 2136-2143.
  3. Wu C-Y, Su T-Y, Wang M-Y, Yang S-F, Mar K*, Hung S-L*. Inhibitory effects of tea catechin epigallocatechin-3-gallate against biofilms formed from Streptococcus mutans and a probiotic lactobacillus strain. Archives of Oral Biology 2018; 94: 69-77.
  4. Lee Y-Y, Lin M-B, Cheng C-F, Chang L-Y, Liu T-Y, Hung S-L*. Inhibitory effects of the areca nut extract on expression of complement receptors and Fc receptors in human neutrophils. Journal of Periodontology 2014; 85(8): 1096-1106.
  5. Hsu M-J, Hung S-L*. Antiherpetic potential of 6-bromoindirubin-3′-acetoxime (BIO-acetoxime) in human oral epithelial cells. Archives of Virology 2013; 158: 1287-1296.
  6. Hung S-L, Chiang H-H, Wu C-Y, Hsu M-J, Chen Y-T*. Effects of herpes simplex virus type 1 infection on immune functions of human neutrophils. Journal of Periodontal Research 2012; 47(5): 635-644.
  7. Ho W-H, Lee Y-Y, Chang L-Y, Chen Y-T, Liu T-Y, Hung S-L*. Effects of areca nut extracts on the apoptosis pathways in human neutrophils. Journal of Periodontal Research 2010; 45(3):412-420.
  8. Hsu M-J, Wu C-Y, Chiang H-H, Lai Y-L, Hung S-L*. PI3K/Akt signaling mediated apoptosis blockage and viral gene expression in oral epithelial cells during herpes simplex virus infection. Virus Research 2010; 153:36-43.
  9. Lai Y-L, Lin J-C, Yang S-F, Liu T-Y, Hung S-L*. Areca nut extracts reduced the intracellular reactive oxygen species and release of myeloperoxidase by human polymorphonuclear leukocytes. Journal of Periodontal Research 2007; 42(1): 69-76.
  10. Hung S-L, Lin Y-J, Chien E-J, Liu W-G, Chang H-W, Liu T-Y, Chen Y-T*. Areca nut extracts-activated secretion of leukotriene B4, and phosphorylation of p38 mitogen-activated protein kinase and elevated intracellular calcium concentrations in human polymorphonuclear leukocytes. Journal of Periodontal Research 2007 42(5):393-401.
  11. Hung S-L, Lee Y-Y, Liu T-Y, Peng J-L, Cheng Y-Y, Chen Y-T*. Modulation of phagocytosis, chemotaxis and adhesion of neutrophils by areca nut extracts. Journal of Periodontology 2006; 77(4): 579-585.
  12. Ling L-J, Ho F-C, Chen Y-T, Holborow DW, Liu T-Y, Hung S-L*. Areca nut extracts modulated expression of alkaline phosphatase and receptor activator of nuclear factor κB ligand in osteoblasts. Journal of Clinical Periodontology 2005; 32(4): 353-359.
  13. Ling L-J, Ho C-C, Wu C-Y, Chen Y-T, Hung S-L*. Association between human herpesviruses and the severity of periodontitis. Journal of Periodontology 2004; 75(11): 1479-1485.
  14. Hung S-L*, Chen Y-L, Wan H-C, Liu T-Y, Chen Y-T, Ling L-J. Effects of areca nut extracts on the functions of human neutrophils in vitro. Journal of Periodontal Research 2000; 35: 186-193.
  15. Hung S-L*, Lee P-L, Chen H-W, Chen L-K, Kao C-L, King C-C. Analysis of the steps involved in Dengue virus entry into host cells. Virology 1999; 257: 156-167.
  16. Hung, S-L, Srinivasan S, Friedman HM, Eisenberg RJ, and Cohen GH. Structural basis of C3b binding by glycoprotein C of Herpes Simplex Virus. Journal of Virology 1992; 66: 4013-4027.
  17. Sethna PB, Hung S-L, Brian DA. Coronavirus subgenomic minus-strand RNAs and the potential for mRNA replicons. Proceedings of the National Academy of Sciences of the United States of America 1989; 86: 5626-5630.
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