Kuo-Wei CHANGDepartment of Dentistry 2026-07-092026-07-13<![CDATA[<style type="text/css">.ed_model11 .job-title {
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<div class="ed_title03">Kuo-Wei CHANG, Professor</div>
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<strong>Email:</strong> <a href="mailto:ckcw@nycu.edu.tw" title="ckcw@nycu.edu.tw">ckcw@nycu.edu.tw</a><br>
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<strong>Phone:</strong> +886-2-2826-7223<br>
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<strong>Office Location:</strong> Room 405, Dentistry Building<br>
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<strong>Specialties:</strong> Oral Pathology, Molecular Pathology, Oral Cancer Research, Cancer Biology<br>
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<div class="ed_txt"><strong>Education</strong></div>
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<li class="ed_txt">Ph.D. in Pathology, Northwestern University, USA</li>
<li class="ed_txt">Residency Training in Oral Pathology, Northwestern University, USA</li>
<li class="ed_txt">Bachelor of Dental Surgery (B.D.S.), National Yang-Ming Medical College</li>
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<strong>Professional Experience</strong></div>
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<li class="ed_txt">Dean, College of Dentistry, National Yang Ming Chiao Tung University</li>
<li class="ed_txt">Director, Institute of Oral Biology, National Yang-Ming University</li>
<li class="ed_txt">President, Chinese Academy of Oral Pathology</li>
<li class="ed_txt">Board-Certified Specialist, Oral Pathology</li>
<li class="ed_txt">Professor, Department of Dentistry, National Yang-Ming University</li>
<li class="ed_txt">Associate Professor, Department of Dentistry, National Yang-Ming University</li>
<li class="ed_txt">Teaching Assistant, Department of Dentistry, National Yang-Ming Medical College</li>
<li class="ed_txt">Research Fellow, Department of Stomatology, Taipei Veterans General Hospital</li>
<li class="ed_txt">Resident, Department of Dentistry, Veterans General Hospital</li>
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<span style="font-size:120%;"><strong>Honors & Achievements</strong></span>
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<li>Convener, Medical Engineering Program, Ministry of Science and Technology (2020–2022)</li>
<li>President's Award, International Association of Oral Pathologists (2018)</li>
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<span style="font-size:120%;"><strong>Representative Publications (Past 5 Years)</strong></span></div>
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<li class="ed_txt">Lin LH, Chang KW, Cheng HW, Liu CJ* (2026, Feb). Profilin-2 promotes tumor aggressiveness in oral squamous cell carcinoma via HDAC1 modulation: implications for EMT and targeted therapy. Br J Cancer, 134: 331-41. NSTC 110-2314-B-195-015-MY3.</li>
<li class="ed_txt">Chang SR, Chou CH, Liu CJ, Chang KW, Pan JH, Yen SL, Lin SC* (2026, Jan). The roles of CD24-Sec14 like lipid binding 2 (SEC14L2) axis in the neoplastic progression of oral squamous cell carcinomas. J Dent Sci, 21(1): 232-243. NSTC 111-2314-B-A49A-025-MY3.</li>
<li class="ed_txt">Chou CH, Chang KW, Hung WW, Wei MA, Liu CJ, Lin SC* (2026, Jan). Apoptosis-inducing factor mitochondria-associated 2 (AIFM2) promotes tumor progression and predicts poor prognosis in oral squamous cell carcinoma. J Dent Sci, 21(1): 541-550. NSTC 114-2811-B-A49A-002.</li>
<li class="ed_txt">Liu YC, Liu SY, Lin YC, Liu CJ, Chang KW, Lin SC* (2024, Sep). The disruption of NEAT1-miR-125b-5p-SLC1A5 cascade defines the oncogenicity and differential immune profile in head and neck squamous cell carcinoma. Cell Death Discovery, 10, 392. NSTC 110-2314-B-A49A-521-MY3.</li>
<li class="ed_txt">Chang SR, Chou CH, Tu HF, Liu CJ, Chang KW*, Lin SC* (2024, Jul). The expression of immune co-stimulators as a prognostic predictor of head and neck squamous cell carcinomas and oral squamous cell carcinomas. J Dent Sci, 19(3):1380-1388. NSTC 108-2314-B-010-010-MY3. (Corresponding author)</li>
<li class="ed_txt">Chou CH, Yen CH, Liu CJ, Tu HF, Lin SC*, Chang KW* (2024, Mar). The upregulation of VGF enhances the progression of oral squamous carcinoma. Cancer Cell International, 24(1):115. NSTC 108-2314-B-010-010-MY3. (Corresponding author)</li>
<li class="ed_txt">Cheng YC, Chang, KW (co-first author), Pan JH, Chen CY, Chou CH, Tu HF, Li WC, Lin SC* (2023, Nov). Cold atmospheric plasma jet irradiation decreases the survival and the expression of oncogenic miRNAs of oral carcinoma cells. Int J Mol Sci, 24, 16662. NSTC 110-2314-B-A49A-515-MY3. (First author)</li>
<li class="ed_txt">Lin LH, Chang KW (co-first author), Cheng HW, Liu CJ* (2023, Aug). Identification of somatic mutations in plasma cell-free DNA from patients with metastatic oral squamous cell carcinoma. Int J Mol Sci, 24(12):10408. (First author)</li>
<li class="ed_txt">Chang SR, Chou CH, Liu CJ, Lin YC, Tu HF, Chang KW*, Lin SC* (2023, Apr). The concordant disruption of B7/CD28 immune regulators predicts the prognosis of oral carcinomas. Int J Mol Sci, 24(6): 5931. NSTC 110-2314-B-195-015-MY3. (Corresponding author)</li>
<li class="ed_txt">Lin SC., Liu CJ, Ji SH, Hung WW, Liu YC, Chang SR, Tu HF, Chang KW* (2022, Feb). The upregulation of oncogenic miRNAs in swabbed samples obtained from oral premalignant and malignant lesions. Clin Oral Investig, 26: 1343-51. MOST 107-2314-B-010-032-MY3. (Corresponding author)</li>
<li class="ed_txt">Chou CH, Fan Chiang CY, Yang CC, Liu YC, Chang SR, Chang KW*, Lin SC* (2021, Oct). miR-31-NUMB cascade modulates Monocarboxylate Transporters to increase oncogenicity and lactate production of oral carcinoma cells. Int J Mol Sci, 22(21):11731. MOST 107-2314-B-010-026-MY3. (Corresponding author)</li>
<li class="ed_txt">Chang KW, Hung WW, Chou CH, Tu HF, Chang SR, Liu YC, Liu CJ, Lin SC* (2021, Aug). LncRNA MIR31HG drives oncogenicity by inhibiting the Limb-Bud and Heart Development gene (LBH) during oral carcinoma. Int J Mol Sci, 21(8383):1-15. MOST 108-2314-B-010-011-MY3. (First author)</li>
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