{"subject":"Ding-Han WANG","pubUnitName":"Institute of Oral Tissue Engineering and Biomaterials","posterDate":"2026-06-25","updateDate":"2026-07-13","detailContent":"\r\n
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\"Ding-Han
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Associate Professor Ding-Han WANG 
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\r\nEmail: dhwang@nycu.edu.tw
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\r\nPhone: +886-2-2826-7913
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\r\nOffice Location: Room 421, Dentistry Building
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Education
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\r\nResearch Positions
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Management Experience
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\r\n2024 - present: Associate Chairperson, National Yang Ming Chiao Tung University
\r\n2024 - present: Associate Executive Director, Office of Sustainable Development and University Social Responsibility
\r\n2023 - present: Secretary-general, Taiwan Dental Sleep Medicine Academy
\r\n2022 - present: Secretary-general, Taiwan Academy of Craniomandibular Disorders
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\r\nPresent Research Activities
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\r\nWelcome to the research laboratory led by Dr. Ding-Han Wang, Associate Professor in the School of Dentistry at National Yang Ming Chiao Tung University. Our lab is dedicated to advancing digital transformations in dentistry and medicine, with a focus on enhancing healthcare outcomes and innovating educational methodologies. By integrating cutting-edge technologies with biological insights, our interdisciplinary team aims to drive progress in diagnostics, therapeutic approaches, and medical education.
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\r\nResearch Areas
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\r\nDigital Development of Tissue Engineering for TMJ Arthritis
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  1. Utilizing digital technologies to develop tissue engineering solutions for the treatment of temporomandibular joint (TMJ) arthritis.
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  2. Conducting basic experimental animal studies and molecular biology research to investigate the underlying mechanisms of temporomandibular joint (TMJ) arthritis.
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\r\nOral Microbiota Research
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  1. Leveraging next-generation sequencing (NGS) and bioinformatics tools to analyze microbial communities and their impact on oral and systemic health.
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  2. Investigating microbiome dynamics in diseases such as periodontal disease and dental caries, with a particular focus on systemic connections in aging populations.
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  3. Developing personalized oral healthcare strategies to improve overall health outcomes.
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\r\nExtended Reality (XR) Technologies in Dental Education and Clinical Applications
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  1. Enhancing dental education by integrating XR technologies.
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  2. Improving clinician-patient decision-making and surgical simulations through XR applications.
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\r\nArtificial Intelligence (AI) Applications in Dentistry
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  1. Examining the impact of background effects on deep learning models for classifying decayed, missing, and filled teeth (DMFT-AI).
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  2. Developing the Index of Orthodontic Treatment Needed (IOTN-AI) model to mimic human decision-making in assessing orthodontic treatment needs.
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  3. Implementing deep learning techniques for the segmentation of maxillofacial anatomical structures on cone-beam computed tomography (CBCT) images.
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  4. Our laboratory is committed to bridging digital innovations and biological research to advance healthcare practices, providing personalized solutions, and supporting the future of dentistry and medicine.
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\r\nScientific Publications
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\r\n39 publications referenced in PubMed, 17 conference proceedings. Science citation index: H-index = 10 in Web of Science (13 in Google Scholar), 423 times cited in Web of Science (699 in Google Scholar).
\r\n2 invention patents (I783528, I857862 in Taiwan). FWCI index: 1.26 (2022-2025).
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\r\nAwards\r\n
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  1. 113學年度輔導境外學生績優教師
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  2. 113學年度績優導師
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  3. 113學年度優良服務學習課程教師
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  4. 2025 Taiwan Sustainable Action Awards (TSAA)：SDG03 Smiles for All, Powered by Technology” – Gold Award
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  5. 2025 Asia-Pacific Sustainable Action Awards (APSAA)：SDG3 Smiles for All, Powered by Technology–Silver Award
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  6. Deep Learning Classification of Decayed-Missing-Filled Tooth Status on Intraoral Photos. 2025 IADR Hatton Competition in the Senior - Clinical Research category – First Place, IADR General Session & Exhibition, July, 2025.
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  7. Digital Transformation of Community Oral Health Education Program. 2025 Global Views University Social Responsibility (USR) Award – First Prize in the \"Collaborative Learning Group\", Taiwan, 2025.
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  8. Multidisciplinary treatment of orofacial pain and cranio-mandibular disorders. 2024 Symbol of National Quality (SNQ) Award-Hospital Category: Specialist Medicine, awarded to Taipei Veterans General Hospital, Taiwan, 2024.
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  9. Background Effects on Deep Learning Classification of Decayed-Missing-Filled Tooth Status. 38th Annual Scientific Meeting of the IADR South-East Asia Division, Malaysia. IADR-Unilever Hatton Award (Senior Category) 1st Prize, 2024.
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  10. Using mobile augmented reality technology supports medical education and shared decision-making. National Innovation Award, 2023.
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  11. \"Hierarchical Panoptic Segmentation of Crops and Weeds\" challenge at the Computer Vision in Plant Phenotyping and Agriculture (CVPPA) - International Conference on Computer Vision (ICCV) 2nd Prize, 2023.
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  12. ZNF582 Methylation and Oral Microbiota in Oral Cancer. 37th Annual Scientific Meeting of the IADR South-East Asia Division, Singapore. IADR-SEA RESEARCH CATEGORY AWARD Oral Microbiology & Cariology 1st Prize, 2023.
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  13. Temporal stability of tongue microbiota in elderly patients. 37th Annual Scientific Meeting of the IADR South-East Asia Division, Singapore. IADR-SEA Hatton Award Competition Senior Category 2nd Prize, 2023.
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  14. Journal of Dental Science (JDS) Excellent Paper Award, October, 2018.
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  15. The J. Morita Post-doctoral Award, 1st Prize, IADR Geriatric Oral Research Awards, July, 2018.
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\r\nPatent  
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  1. Ding-Han Wang, Yi-Tzu Cheng, Yen-Lin Chen, Jian-Quan Su, Chun-Yen LU. Portable dental teaching device integrating virtual and real scenes, portable dental teaching aids, dental teaching method and computer program product thereof (I857862, Taiwan).
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  2. Ding-Han Wang, Chun-Yen LU, Ming-Lun Hsu, Yi-Chen Hsu, Ngoc Trang Tran Thi, Juin-Hong Cherng, Po-Han Wu, Chia-Yu lin. Portable Medical Education Device, Medical Education Platform, and Medical Education Methods. (I783528, Taiwan).
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\r\nPublication List
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  1. Yung-Chang Lu*, Ding-Han Wang*, Ting-Kuo Chang, Shu-Ting Yeh, Tzu-Chiao Lin, Chun-Hsiung Huang, Chang-Hung Huang. (2026, Mar). Mechanical strength and osteogenic potential for biomedical metals with diamond-like carbon surface coating. Surf Coat Technol.
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  2. Cheng-Pei Lin, Lu-Yen Anny Chen, Yu-Chi Chen, Jou-Chun Lin, Ding-Han Wang, Heng-Hsin Tung. (2026, Feb). Feasibility and Acceptability of Immersive Virtual Reality for End-of-Life Care Education Among Nurses in High-Context Cultures. Nurse Educ Pract.
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  3. Moumita Deb, Chang-Chuan Huang, Yen-Ming Lai, Chang-Ju Chu, Yu-Shan Lee, Chien-Ting Chen, William Lee, Hsin-Fei Meng, Li-Yin Chen, Olivier Soppera, Chao-Sung Lai, Ding-Han Wang*, Chia-Jung Lu*, Hsiao-Wen Zan*. (2025, Dec). CuO/PVA-based ultra-low-volume oral H2S detection system to reveal tongue coating effects. Chem Eng J.
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  4. Anand Marya, Siddharthan Selvaraj, Katsushi Okazaki, Ding-Han Wang, Hiroyasu Kanetaka, Thantrira Porntaveetus. (2025, Dec). The Role of Extended Reality in Orthodontic Treatment Planning and Simulation-A scoping Review. Int Dent J. 75(6):103855.
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  5. Hong Thi-Phuong Doan, Khoa Dang Nguyen, Yu-Min Lin, Guang Hong, Ming-Lun Hsu*, Ding-Han Wang*. (2025, Nov). Comparison of stereolithography (STL) and polygon file format (PLY) for intraoral scans: From chairside to archive. J Dent.
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  6. Ying-Shian Chen, Yi-Chen Hsu, Worachate Romalee, Ding-Han Wang, Jennifer Lai, Tsai-Wang Huang, Kuan Hsun Lin. (2025, Nov). Effect of Mobile Augmented Reality Counseling on Improving Shared Decision-Making in Thoracic Surgery: Randomized Clinical Crossover Trial. JMIR Mhealth Uhealth. 13:13:e79632
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  7. Chia-Chun Chen, Tran-Thi-Ngoc Trang, Ding-Han Wang*, Nien-Ti Tsou*. (2025, July). A numerical approach to bio-mechanics analysis based on live micro-CT images in the rat temporomandibular joint. Comput Struct Biotechnol J. Volume 27, 2025, Pages 2946-2954.
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  8. Nguyen Chi Tran, Nhat Dinh Minh Nguyen, Nam Cong Nhat Huynh, Trang Thi Ngoc Tran, Hung Trong Hoang, Ding Han Wang, Ming Lun Hsu. (2025, Apr). Influence of composite resin core buildup translucency on the accuracy of an anterior CAD-CAM bridge fabricated with a digital impression. J Clin Exp Dent. 2025 Ap 1;17(4):e366-e373.
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  9. Cheng‐Chieh Yang, Jumpei Washio, Yu‐Cheng Lin, Ming‐Lun Hsu, Ding‐Han Wang, Fa‐Tzu Tsai, Yu‐Min Lin, Hsi‐Feng Tu, Hsiu‐Chuan Chang, Nobuhiro Takahashi. (2025, Apr). Microbiome Signatures and Dysbiotic Patterns in Oral Cancer and Precancerous Lesions. doi: 10.1111/odi.15317.
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  10. Khoa Dang Nguyen, Hung Trong Hoang, Hong Thi-Phuong Doan, Khai Quang Dao, Ding-Han Wang*, Ming-Lun Hsu*. (2025, Apr). SegmentAnyTooth: An open-source deep learning framework for tooth enumeration and segmentation in intraoral photos. J Dent Sci. 20(2):1110-1117.
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  11. Ding-Han Wang, Kim-Xuyen Nguyen, Trang Thi-Ngoc Tran, Po-Han Wu, Guang Hong, Yu-Min Lin, Yi-Chen Hsu, Cheng-Chieh Yang, Yu-Cheng Lin, Wun-Eng Hsu, Ming-Lun Hsu, Mu-Chen Yang. (2025, Jan). Phosphotungstic acid-enhanced micro-computed tomography and RNA sequencing provide a new perspective on temporomandibular joint arthritis induced by complete Freund's adjuvant and collagen-induced arthritis in rat models. J Dent Sci. 20(1):189-200.
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  12. Yen-Thi Le, Nguyen-Chi Tran, Ding-Han Wang, Ming-Lun Hsu. (2024, Jun). Correlation of resin composite translucency and IOS accuracy: An in-vitro study. J Clin Exp Dent. 2024 Jun 1;16(6):e678-e684.
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  13. Fa-Tzu Tsai, Cheng-Chieh Yang, Yu-Cheng Lin, Ming-Lun Hsu, Guang Hong, Mu-Chen Yang, Ding-Han Wang, Lin-Jack Huang, Chiu-Tzu Lin, Wun-Eng Hsu, Hsi-Feng Tu. (2024, Apr). Temporal stability of tongue microbiota in older patients – A pilot study. Journal of Dental Sciences. nstc 112-2314-B-A49-058.
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  14. Worachate Romalee, Nattira Suksudaj, Patchayaporn Doungkom, Ding-Han Wang, Ming-Lun Hsu, Piyaphong Panpisut (2024, Mar). Utilization of 3D evaluation for assessing selective caries removal practice in pre-clinical dental students: a pilot study. BMC Medical Education. 15;24(1):289.
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  15. Worachate Romalee, Fa-Tzu Tsai, Yi-Chen Hsu, Ming-Lun Hsu*, Ding-Han Wang* (2024, Feb). Effectiveness of mobile augmented reality–integrated oral health education for community-dwelling older adults: A randomized controlled trial. Archives of Gerontology and Geriatrics, Oct;18(4):1838-1844. nstc 112- 2314-B-A49-058.
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  16. Ding-Han Wang, Fa-Tzu Tsai, Hsi-Feng Tu, Cheng-Chieh Yang, Ming-Lun Hsu, Lin-Jack Huang, Chiu-Tzu Lin, Wun-Eng Hsu, Yu-Cheng Lin (2023, Feb). Profiles of oral microbiome associated with nasogastric tube feeding. Journal of Oral Microbiology, 15(1): 2200898. nstc 111-2314-B-A49-033.
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  17. Wei-Jyun Hua, Hsin Yeh, Zhi-Hu Lin, Ai-Jung Tseng, Li-Chen Huang, Wei-Lun Qiu, Tsung-Hsi Tu, Ding-Han Wang, Wei-Hung Hsu, Wei-Lun Hwang, Tung-Yi Lin (2023, Dec). Ganoderma microsporum immunomodulatory protein as an extracellular epidermal growth factor receptor (EGFR) degrader for suppressing EGFR-positive lung cancer cells. Cancer Letters, Volume 578, 1.
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  18. Worachate Romalee, Fa-Tzu Tsa, Yi-Chen Hsu, Ming-Lun Hsu*, Ding-Han Wang* (2023, Oct). A mobile augmented reality-integrated oral health education for community-dwelling older adults: a pilot study. Journal of Dental Sciences. nstc 111-2314-B-A49-033.
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  19. Nhat Dinh-Minh Nguyen, Nguyen Chi Tran, Trang Thi-Ngoc Tran, Nam Cong-Nhat Huynh, Khoa Dang Nguyen, Hung Trong Hoang, Ding-Han Wang, Ming- Lun Hsu (2023, Jul). Effects of core buildup composite resin translucency on intraoral scanner accuracy: an in vitro study. International Journal of Computerized Dentistry, Vol. 26 Issue 3, p201-210. 10p. nstc 111-2314-B-A49- 033.
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  20. Trang Thi Ngoc Tran*, Ding-Han Wang*, Mu-Chen Yang, Jyh-Cheng Chen, Po- Han Wu, Cheng-Chieh Yang, Wun-Eng Hsu, Ming-Lun Hsu. (2023, Feb). Effects of food hardness on temporomandibular joint osteoarthritis: Qualitative and quantitative micro-CT analysis of rats in vivo. Annals of Anatomy, 23;246:152029. nstc 111-2314-B-A49-033.
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  21. Tzu-En Lin, Ming-Chun Chien, Po-Feng Chen, Pei-Wen Yang, Huai-En Chang, Ding-Han Wang, Tung-Yi Lin, and Yung-Jung Hsu. (2022, Nov). A Sensor- Integrated Face Mask Using Au@SnO2 Nanoparticle Modified Fibers and Augmented Reality Technology. ACS Omega, 22; 7(46): 42233–42241.
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  22. Zih-Kai Kao, Neng-Tai Chiu, Hung-Ta Hondar Wu, Wan-Chen Chang, Ding-Han Wang, Yen-Ying Kung, Pei-Chi Tu, Wen-Liang Lo, Yu-Te Wu. (2022, Aug). Classifying Temporomandibular Disorder with Artificial Intelligent Architecture Using Magnetic Resonance Imaging. Annals of Biomedical Engineering.
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  23. Worachate Romalee, Matana Kettratad, Tran Thi NgocTrang, Ding-Han Wang, Jia-En Chen, Ming-Lun Hsu. (2022, Apr). Evaluation of the potential denture covering area in buccal shelf with intraoral scanner. Journal of Dental Sciences.
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  24. Fa-Tzu Tsai*, Ding-Han Wang*, Cheng-Chieh Yang, Yu-Cheng Lin, Lin-Jack Huang, Wei-Yu Tsai, Chang-Wei Li, Wun-Eng Hsu, Hsi-Feng Tu, Ming-Lun Hsu. (2022, Feb). Locational effects on oral microbiota among long-term care patients. Journal of Oral Microbiology, 14(1): 2033003.
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  25. Yee-Fun Su, Yi-Ju Chen, Fa-Tzu Tsai, Wan-Chun Li, Ming-Lun Hsu, Ding-Han Wang and Cheng-Chieh Yang (2021, Jul). Current Insights into Oral Cancer Diagnostics. Diagnostics, 11(7), 1287.
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  26. Chia-Yu Wang, Po-Da Hong, Ding-Han Wang, Juin-Hong Cherng, Shu-Jen Chang, Cheng-Che Liu, Tong-Jing Fang, Yi-Wen Wang. (2020, Nov). Polymeric Gelatin Scaffolds Affect Mesenchymal Stem Cell Differentiation and Its Diverse Applications in Tissue Engineering. International Journal of Molecular Sciences, 16;21(22): E8632.
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  27. Jue-Zong Yeh*, Ding-Han Wang*, Juin-Hong Cherng, Yi-Wen Wang, Gang-Yi Fan, Nien-Hsien Liou, Jiang-Chuan Liu, Chung-Hsing Chou. (2020, Sep). A Collagen-Based Scaffold for Promoting Neural Plasticity in a Rat Model of Spinal Cord Injury. Polymers.
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  28. Dewi Sartika, Chih-Hsin Wang, Ding-Han Wang, Juin-Hong Cherng, Shu-Jen Chang, Gang-Yi Fan, Yi-Wen Wang, Chian-Her Lee, Po-Da Hong, Chih-Chien Wang. (2020, Apr). Human Adipose-Derived Mesenchymal Stem Cells- Incorporated Silk Fibroin as a Potential Bio-Scaffold in Guiding Bone Regeneration. Polymers, 12(4):853.
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  29. Kuang‐Ta Yao, Tsai‐Yu Chang, Hsu‐Wei Fang, Chang‐Hung Huang, Ding-Han Wang, Ming‐Lun Hsu. (2019, Oct). Abutment screw withdrawal after conical abutment settlement: A pilot study. Clinical Oral Implants Research.
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  30. Chia-Yu Wang, Dewi Sartika, Ding-Han Wang, Po-Da Hong, Juin-Hong Cherng, Shu-Jen Chang, Cheng-Che Liu, Yi-Wen Wang, Sheng-Tang Wu. (2019, Mar). Wet-spinning-based Molding Process of Gelatin for Tissue Regeneration. Jove- Journal of Visualized Experiments, 7;(145).
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  31. Mu-Chen Yang, Ding-Han Wang, Hung-Ta Wu, Wan-Chun Li, Tsai-Yu Chang, Wen-Liang Lo, Ming-Lun Hsu (2019, Feb). Correlation of magnetic resonance imaging grades with cytokine levels of synovial fluid of patients with temporomandibular joint disorders: A cross-sectional study. Clinical Oral Investigations.
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  32. Chia-Shu Lin, Ching-Yi Wu, Ding-Han Wang, Hsiao-Han Lin, Kuang-Chuan Lo, Wen-Liang Lo, Li-Kuo Liu, Jong-Ling Fuh, Ming-Lun Hsu (2019, Jan). Brain signatures associated with swallowing efficiency in older people. Experimental Gerontology, 115:1-8.
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  33. Mu-Chen Yang*, Ding-Han Wang*, Juin-Hong Cherng, Wan-Chun Li, Po-Yen Lin, Wun-Eng Hsu, Ming-Lun Hsu. (2019, Jan). Role of Link N in modulating inflammatory conditions. J Oral Facial Pain Headache, 33(1):114-122.
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  34. Wen-Liang Lo, Hsin-Bang Leu, Mu-Chen Yang, Ding-Han Wang, Ming-Lun Hsu (2019, Jan). Dysphagia and risk of aspiration pneumonia: A nonrandomized, pair-matched cohort study. Journal of Dental Sciences.
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  35. Chih-Ling Chang, Ding-Han Wang, Mu-Chen Yang, Wun-Eng Hsu, Ming-Lun Hsu. (2018, Apr). Functional disorders of the temporomandibular joints: Internal derangement of the temporomandibular joint. Kaohsiung Journal of Medical Sciences, 34(4):223-230.
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  36. Tong-Jing Fang, Ding-Han Wang, Chia-Yu Wang, Raju Poongodi, Nien-Hsien Liou, Jiang-Chuan Liu, Ming-Lun Hsu, Po-Da Hong, Shih-Fang Yang, Meng-Lun Liu. Osteogenic prospective of deriving human dental stem cells in collagen matrix boost. J Mater Sci Mater Med. 2017 Nov 15;28(12):192.
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  37. Ding-Han Wang, Mu-Chen Yang, Wun-Eng Hsu, Ming-Lun Hsu, Ling-Ming Yu. Response of the temporomandibular joint tissue of rats to rheumatoid arthritis induction methods. J Dent Sci. 2017 Mar;12(1):83-90.
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  38. Shu-Jen Chang, Juin-Hong Cherng, Ding-Han Wang, Shu-Ping Yu, Nien-Hsien Liou, Ming-Lun Hsu. Transneuronal degeneration of thalamic nuclei following middle cerebral artery occlusion in rats. Biomed Res Int. 2016:2016:3819052.
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  39. Ding-Han Wang, Mu-Chen Yang, Wun-Eng Hsu, Ming-Lun Hsu. Comparison of Three Techniques for Swine Temporomandibular Joint Space Injection. J Oral Facial Pain Headache. 2016 Spring;30(2):165-70.
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